4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178518110, compound

Participants

Reaction Steps

To a solution of [1-(aminomethyl)cyclobutyl]methanol (1.00 g) in ethanol (30 mL) was added 4-thioxo-1,3-thiazolidin-2-one (1.16 g), and the mixture was heated under reflux overnight. The reaction mixture was concentrated under reduced pressure, and the obtained powder was washed with ethyl acetate to give the title compound (795 mg).

Provenance & Evidence