Dimethylamine → HCID 86678841, compound

Participants

Reaction Steps

To a solution of N-carbobenzoxy-L-serine (5.00 g) in ethanol (70 mL) were added dimethylamine (2.51 mL) and 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride n-hydrate (6.23 g), and the mixture was stirred at room temperature overnight. The reaction mixture was concentrated under reduced pressure, and the residue was dissolved in ethyl acetate/tetrahydrofuran and water. The organic layer was separated, washed with water and saturated brine, dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure to give the title compound (3.23 g).

Provenance & Evidence