4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178484588, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of N,N-dimethyl-L-serinamide (1.61 g) in ethanol (50 mL) was added 4-thioxo-1,3-thiazolidin-2-one (1.63 g), and the mixture was stirred at 70° C. overnight. The reaction mixture was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (NH, methanol/ethyl acetate) to give the title compound (1.53 g).

Provenance & Evidence