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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1620701Generated: October 30, 2026

4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178495732, compound

https://huagongshe.com/reaction/1620701

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Sulfanylidene-1,3-thiazolidin-2-oneHCID 1539595—
ReactantHCID 86678862HCID 86678862—
SolventEthanolHCID 702—
ProductHCID 178495732HCID 17849573223.6%

Reaction Steps

To a solution of 4-thioxothiazolidin-2-one (1.00 g) in ethanol (20 mL) was added N,N,O-trimethyl-L-serinamide (1.82 g) at room temperature. The reaction mixture was stirred at room temperature overnight, and the solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (434 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08772277B2
Source datasetuspto-grants-2014_07
ORD IDord-68be9bbdcf6f4b11a65b0118185e69b2
Source noteuspto-grants-2014_07