HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178496742, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Sulfanylidene-1,3-thiazolidin-2-one | HCID 1539595 | — |
| Reactant | (2S,3R)-2-amino-3-methoxy-N,N-dimethyl-butanamide | HCID 86678876 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178496742 | HCID 178496742 | 35.1% |
Reaction Steps
To a solution of N,N,O-trimethyl-L-threoninamide (1198 mg) in ethanol (10 mL) was added 4-thioxothiazolidin-2-one (996 mg) at room temperature. The reaction mixture was stirred at room temperature overnight, the solvent was evaporated under reduced pressure, and the residue was purified by silica gel column chromatography (NH, ethyl acetate/hexane) to give the title compound (680 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772277B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-d7bce9d44053494ab92402ebe4a71ecc |
| Source note | uspto-grants-2014_07 |