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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1620767Generated: October 31, 2026

4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178484594, compound

https://huagongshe.com/reaction/1620767

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Sulfanylidene-1,3-thiazolidin-2-oneHCID 1539595—
ReactantHCID 86678927HCID 86678927—
SolventEthanolHCID 702—
ProductHCID 178484594HCID 17848459413.3%

Reaction Steps

To a solution of (2S)-2-amino-2-(1-hydroxycyclopropyl)-N,N-dimethylethanamide (60 mg) in ethanol (1 mL) was added 4-thioxothiazolidin-2-one (51 mg) at room temperature. The reaction mixture was stirred at room temperature overnight, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (NH, ethyl acetate/hexane) to give the title compound (13 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08772277B2
Source datasetuspto-grants-2014_07
ORD IDord-8bb18b8ad1ee4d2f9998126d4e1bb74a
Source noteuspto-grants-2014_07