HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Sulfanylidene-1,3-thiazolidin-2-one → HCID 178484594, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Sulfanylidene-1,3-thiazolidin-2-one | HCID 1539595 | — |
| Reactant | HCID 86678927 | HCID 86678927 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178484594 | HCID 178484594 | 13.3% |
Reaction Steps
To a solution of (2S)-2-amino-2-(1-hydroxycyclopropyl)-N,N-dimethylethanamide (60 mg) in ethanol (1 mL) was added 4-thioxothiazolidin-2-one (51 mg) at room temperature. The reaction mixture was stirred at room temperature overnight, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (NH, ethyl acetate/hexane) to give the title compound (13 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772277B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-8bb18b8ad1ee4d2f9998126d4e1bb74a |
| Source note | uspto-grants-2014_07 |