HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyltributylstannane → HCID 86685237, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyltributylstannane | HCID 90628 | — |
| Reactant | Ethyl 3,4-dichlorophenylglyoxylate | HCID 2736412 | — |
| Catalyst | Titanium Tetrachloride | HCID 24193 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86685237 | HCID 86685237 | 77% |
Reaction Steps
To the solution of ethyl 2-(3,4-dichlorophenyl)-2-oxoacetate (100 g, 3.8 mol) in CH2Cl2 was added allyltributyltin (1.2 equivalents) and TiCl4 (1.2 equivalents) at 0° C. and mixture was stirred for 40 hours at 0° C. to room temperature. Purification by chromatography on silica gel provided title compound (90 g, 77%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772500B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-0c2ae64b9eb9488ca313888349ff506c |
| Source note | uspto-grants-2014_07 |