Azetidine → 5-(Azetidine-1-carbonyl)-2-chloro-3-methyl-3H-imidazole-4-carboxylic acid [2-(1-methyl-1H-benzoimidazol-2-yl)-ethyl]-amide

Participants

Reaction Steps

The product was obtained starting from 2-chloro-1-methyl-5-(2-(1-methyl-1H-benzo[d]imidazol-2-yl)ethylcarbamoyl)-1H-imidazole-4-carboxylic acid (30 mg, 82.9 μmol) and azetidine (14.2 mg, 16.9 μl, 249 μmol) according to the method described in example 7, step 5 as white waxy solid (17.5 mg, 41.5 μmol, 50.0%). MS: M=401.2 (M+H)+

Provenance & Evidence