HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzaldehyde → 6-Fluoro-2-[(4-methoxyphenyl)methyl]isoquinolin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzaldehyde | HCID 68023 | — |
| Reactant | 7-Chloro-6-fluoro-2-[(4-methoxyphenyl)methyl]isoquinolin-1(2H)-one | HCID 59818247 | — |
| Product | 6-Fluoro-2-[(4-methoxyphenyl)methyl]isoquinolin-1-one | HCID 59818260 | — |
Reaction Steps
Starting from 4-fluoro benzaldehyde, the title compound was prepared following a similar sequence as described for 7-chloro-6-fluoro-2-(4-methoxy-benzyl)-2H-isoquinolin-1-one (62). Rt=1.72 min (Method B). Detected mass: 284.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08772492B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-8aefff3168e546feb4473dd1e5cb1c9c |
| Source note | uspto-grants-2014_07 |