2,5-Pyridinediamine → N5-(3-(4-Amino-6-methyl-1,3,5-triazin-2-YL)pyridin-2-YL)pyridine-2,5-diamine

Participants

Reaction Steps

The title compound was prepared following the procedure of Example 49, utilizing 4-(2-fluoropyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine and 2,5-diaminopyridine (Aldrich). LCMS (API-ES) m/z 295 (M+H)+. 1H NMR (400 MHz, d6-DMSO) δ 11.52 (s, 1H); 8.75 (d, J=7.83 Hz, 1H); 8.74 (dt, J=7.83, 1.08 Hz, 1H); 8.34 (d, J=2.74 Hz, 1H); 8.27 (d, J=1.76 Hz, 1H); 8.26 (d, J=2.15 Hz, 1H); 7.87 (d, J=8.80 Hz, 1H); 7.88 (dt, J=9.00, 1.08 Hz, 1H); 7.68 (br. s., 1H); 6.83 (dd, J=7.82, 4.70 Hz, 1H); 6.62 (d, J=8.80 Hz, 1H); 2.42 (s, 3H).

Provenance & Evidence