HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-tert-butyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide → N-acetyl-N'-tert-butyl-5-formyl-6-methoxy-biphenyl-3,3'-disulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-tert-butyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide | HCID 58169119 | — |
| Reactant | N-acetyl-5-bromo-3-formyl-4-methoxybenzenesulfonamide | HCID 86607697 | — |
| Product | N-acetyl-N'-tert-butyl-5-formyl-6-methoxy-biphenyl-3,3'-disulfonamide | HCID 86607706 | 51.6% |
Reaction Steps
Proceeding as in Reference 19, but substituting N-acetyl-3-bromo-5-formyl-4-methoxy-benzenesulfonamide (335 mg, 1.0 mmol) and N-tert-butyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzenesulfonamide (373 mg, 1.1 mmol), gave N-acetyl-N′-tert-butyl-5-formyl-6-methoxy-biphenyl-3,3′-disulfonamide (242 mg) as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08778625B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-de2c6ce16a994ba194ae7bae58460d7e |
| Source note | uspto-grants-2014_07 |