Benzenepropanoyl chloride → N-(3-phenylpropionyl)-3'-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide

HRID 1622136Notes

Reaction equation

HRID 1622136 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:13]([O:14][CH3:15])=[C:12]([CH:16]=[O:17])[CH:11]=[C:10]([S:18]([NH2:21])(=[O:20])=[O:19])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[C:22]1([CH2:28][CH2:29][C:30](Cl)=[O:31])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[C:22]1([CH2:28][CH2:29][C:30]([NH:21][S:18]([C:10]2[CH:9]=[C:8]([C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([NH2:1])[CH:3]=3)[C:13]([O:14][CH3:15])=[C:12]([CH:16]=[O:17])[CH:11]=2)(=[O:19])=[O:20])=[O:31])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 64801Benzenepropanoyl chlorideHCID 866077123'-Amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide

Product 1

HCID 86607719N-(3-phenylpropionyl)-3'-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide

Procedure

Proceeding as in Reference 21, but substituting 3′-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide and 3-phenylpropionyl chloride, gave N-(3-phenylpropionyl)-3′-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide.

Sources & evidence

ORD record
ord-103382f7226a4795b7677d93590cd4cd
Source dataset
uspto-grants-2014_07
Patent number
US08778625B2

Reaction notes

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