HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Diaminobenzimidamide hydrochloride → HCID 178511950, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Diaminobenzimidamide hydrochloride | HCID 22125532 | — |
| Reactant | 6-Benzyloxy-5'-fluoro-5-formyl-2'-methoxybiphenyl-3-carboxylic acid methyl ester | HCID 86607701 | — |
| Product | HCID 178511950 | HCID 178511950 | 58.2% |
Reaction Steps
Proceeding as in Reference 23, but substituting 6-benzyloxy-5′-fluoro-5-formyl-2′-methoxybiphenyl-3-carboxylic acid methyl ester (1.3 g, 3.30 mmol) and 3,4-diaminobenzamidine hydrochloride (0.739 g, 3.96 mmol), gave 5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5′-fluoro-6,2′-dihydroxy-biphenyl-3-carboxylic acid (0.780 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08778625B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-b398b02ca1f04ae99dfbed1236c74d95 |
| Source note | uspto-grants-2014_07 |