HCID 86675674, compound → HCID 71208587, compound

HRID 1622256Notes

Reaction equation

HRID 1622256 reaction equation
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:12]=[C:13]3[CH2:19][CH:18]([CH:20]4[CH2:25][CH2:24][N:23]([C:26]#[N:27])[CH2:22][CH2:21]4)[O:17][C:14]3=[CH:15][N:16]=2)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[OH:28][NH:29][C:30](=N)[CH2:31][CH2:32][CH3:33]>>[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:12]=[C:13]3[CH2:19][CH:18]([CH:20]4[CH2:25][CH2:24][N:23]([C:26]5[O:28][N:29]=[C:30]([CH2:31][CH2:32][CH3:33])[N:27]=5)[CH2:22][CH2:21]4)[O:17][C:14]3=[CH:15][N:16]=2)=[CH:7][CH:6]=1)(=[O:3])=[O:4]

Participants

3

Reactant 2

HCID 86675674HCID 86675674, compoundHCID 178449909HCID 178449909, compound

Product 1

HCID 71208587HCID 71208587, compound

Procedure

The title compound is prepared from 4-[5-(4-methanesulfonyl-phenyl)-2,3-dihydro-furo[2,3-c]pyridin-2-yl]-piperidine-1-carbonitrile and N-hydroxy-butyramidine following a procedure analogous to that described in Example 2. LC (method 5): tR=1.15 min; Mass spectrum (ESI+): m/z=469 [M+H]+.

Sources & evidence

ORD record
ord-b41f43e947be468fb3b0fafbd0febab9
Source dataset
uspto-grants-2014_07
Patent number
US08778926B2

Reaction notes

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