HCID 89372981, compound → HCID 71208089, compound

HRID 1622263Notes

Reaction equation

HRID 1622263 reaction equation
[CH3:1][S:2]([CH2:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:13]=[C:14]3[CH2:20][CH:19]([CH:21]4[CH2:26][CH2:25][N:24]([C:27]#[N:28])[CH2:23][CH2:22]4)[O:18][C:15]3=[CH:16][N:17]=2)=[CH:8][CH:7]=1)(=[O:4])=[O:3].[OH:29][NH:30][C:31](=N)[CH2:32][CH2:33][CH3:34]>>[CH3:1][S:2]([CH2:5][C:6]1[CH:7]=[CH:8][C:9]([C:12]2[CH:13]=[C:14]3[CH2:20][CH:19]([CH:21]4[CH2:26][CH2:25][N:24]([C:27]5[O:29][N:30]=[C:31]([CH2:32][CH2:33][CH3:34])[N:28]=5)[CH2:23][CH2:22]4)[O:18][C:15]3=[CH:16][N:17]=2)=[CH:10][CH:11]=1)(=[O:3])=[O:4]

Participants

3

Reactant 2

HCID 89372981HCID 89372981, compoundHCID 178449909HCID 178449909, compound

Product 1

HCID 71208089HCID 71208089, compound

Procedure

The title compound is prepared from 4-[5-(4-methanesulfonylmethyl-phenyl)-2,3-dihydro-furo[2,3-c]pyridin-2-yl]-piperidine-1-carbonitrile and N-hydroxy-butyramidine following a procedure analogous to that described in Example 2. LC (method 6): tR=1.46 min; Mass spectrum (ESI+): m/z=483 [M+H]+.

Sources & evidence

ORD record
ord-eecda8e494fd4956bb877afbd051822e
Source dataset
uspto-grants-2014_07
Patent number
US08778926B2

Reaction notes

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