HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-ethylpyrimidine → HCID 71208370, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-ethylpyrimidine | HCID 3572763 | — |
| Reactant | (R)-5-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-2-piperidin-4-yl-2,3-dihydro-furo[2,3-c]pyridine | HCID 71208337 | — |
| Product | HCID 71208370 | HCID 71208370 | — |
Reaction Steps
The title compound is prepared from (R)-5-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-2-piperidin-4-yl-2,3-dihydro-furo[2,3-c]pyridine (Intermediate 39, the configuration of the stereocenter is arbitrarily assigned) and 2-chloro-5-ethylpyrimidine following a procedure analogous to that described in Example 1. LC (method 5): tR=0.87 min; Mass spectrum (ESI+): m/z=470 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08778926B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-30607e7aea184ed18d49d6fdd176481b |
| Source note | uspto-grants-2014_07 |