Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1622277Generated: October 30, 2026

2-Chloro-5-ethylpyrimidine → HCID 71208370, compound

https://huagongshe.com/reaction/1622277

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-ethylpyrimidineHCID 3572763—
Reactant(R)-5-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-2-piperidin-4-yl-2,3-dihydro-furo[2,3-c]pyridineHCID 71208337—
ProductHCID 71208370HCID 71208370—

Reaction Steps

The title compound is prepared from (R)-5-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-2-piperidin-4-yl-2,3-dihydro-furo[2,3-c]pyridine (Intermediate 39, the configuration of the stereocenter is arbitrarily assigned) and 2-chloro-5-ethylpyrimidine following a procedure analogous to that described in Example 1. LC (method 5): tR=0.87 min; Mass spectrum (ESI+): m/z=470 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778926B2
Source datasetuspto-grants-2014_07
ORD IDord-30607e7aea184ed18d49d6fdd176481b
Source noteuspto-grants-2014_07