Potassium Carbonate → HCID 71208547, compound

Participants

Reaction Steps

The title compound is prepared from (S)-5-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-2-piperidin-4-yl-2,3-dihydro-furo[2,3-c]pyridine (Intermediate 37, the configuration of the stereocenter is arbitrarily assigned) and 2-chloro-5-(trifluoromethyl)pyrimidine in dimethylsulfoxide at 110° C. in the presence of potassium carbonate. LC (method 5): tR=1.28 min; Mass spectrum (ESI+): m/z=510 [M+H]+.

Provenance & Evidence