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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 162231Generated: October 27, 2026

2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[5-(hydroxymethyl)-6-(morpholin-4-ylmethyl)pyridin-2-yl]amino}thiophene-3-carboxamide

https://huagongshe.com/reaction/162231

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 58216638—
Reactant[6-Chloro-2-(morpholin-4-ylmethyl)pyridin-3-yl]methanolHCID 59525665—
Product5-[2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[5-(hydroxymethyl)-6-(morpholin-4-ylmethyl)pyridin-2-yl]amino}thiophene-3-carboxamideHCID 59525864—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-47dbfabc06f7476ca117cb08630ac498
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)