Methanol → N,N-dimethylpiperidine-4-carboxamide

Participants

Reaction Steps

General procedure B was followed using tert-butyl-4-(dimethylcarbamoyl)piperidine-1-carboxylate 2 (0.16 g, 0.60 mmol), MeOH (2.5 mL) and a 4 M solution of hydrogen chloride in 1,4-dioxane (2.5 mL) to furnish the title compound as a pale yellow oil (67 mg, 71%), umax (CHCl3)/cm−1 3003, 2947, 1625, 1497, 1401, 1320, 1240, 1137, 1105; m/z (ESI) C8H17N2O requires 157.1335, found [M+H]+ 157.1338.

Provenance & Evidence