Triethylamine → HCID 45274905, compound

Participants

Reaction Steps

General procedure C was followed using N,N-dimethylpiperidine-4-carboxamide 6 (43 mg, 0.27 mmol), 3,4,5-trichloropyridine (50 mg, 0.27 mmol), triethylamine (76 μL, 0.54 mmol) and NMP (1.5 mL). The crude product was purified by flash column chromatography on silica gel (hexane/EtOAc, 1:1) to furnish the title compound as a white solid (66 mg, 80%), m.p. 120-122° C.; umax (CHCl3)/cm−1 3026, 2850, 1631, 1559, 1140, 1092, 934; m/z (ESI) C13H18Cl2N3O requires 302.0821, found [M+H]+ 302.0823.

Provenance & Evidence