Triethylamine → HCID 45275017, compound

Participants

Reaction Steps

General procedure C was followed using 4-benzoylpiperazine 10 (47 mg, 0.25 mmol), 3,4,5-trichloropyridine (72 mg, 0.39 mmol), triethylamine (0.11 mL, 0.78 mmol) and NMP (1.5 mL). The crude product was purified by flash column chromatography on silica gel (hexane/EtOAc, 1:1) to furnish the title compound as a white solid (19 mg, 23%), m.p. 132-134° C.; umax (CHCl3)/cm−1 3005, 1627, 1435, 1286, 1153, 1010; m/z (ESI) C16H16Cl2N3O requires 336.0665, found [M+H]+ 336.0661.

Provenance & Evidence