Acetate → Methyl 4-[(4-ethylphenyl)amino]-5-methylthiothiophene-2-carboxylate

HRID 162295Notes

Reaction equation

HRID 162295 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:8](=[S:9])[O:10][CH3:11])[s:5][c:6]1[CH3:7].[C:12](=[O:13])([O-:14])[O-:15].[CH2:18]([CH3:19])[c:20]1[cH:21][cH:22][c:23]([NH2:24])[cH:25][cH:26]1.[Cs+:16].[Cs+:17].[O-:28][C:29]([CH3:30])=[O:31].[O-:32][C:33]([CH3:34])=[O:35].[Pd+2:27]>>[c:2]1([NH:24][c:23]2[cH:22][cH:21][c:20]([CH2:18][CH3:19])[cH:26][cH:25]2)[cH:3][c:4]([C:8](=[S:9])[O:10][CH3:11])[s:5][c:6]1[CH3:7]

Participants

7

Reactant 6

HCID 175Acetate2×HCID 115044-EthylanilineHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 86583861Methyl 4-bromo-5-methylthiothiophene-2-carboxylate

Product 1

HCID 86583863Methyl 4-[(4-ethylphenyl)amino]-5-methylthiothiophene-2-carboxylate

Sources & evidence

ORD record
ord-731bf02154944d7ebd743a4b3c6efe81
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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