HCID 86052868, compound → HCID 86612250, compound

Participants

Reaction Steps

A modification of the general procedure of Part E of Example 6 was followed to treat 5-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)pentan-2-one O-methyloxime (4.6 g, 14.17 mmol) in lieu of 4-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)butyraldehyde O-methyloxime. Purification with flash column chromatography on silica gel (eluting with 5% methanol in dichloromethane) afforded 2.81 g of O-methyl-N-[1-methyl-4-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]hydroxylamine.

Provenance & Evidence