Hydroxyamine hydrochloride → HCID 72448478, compound

Participants

Reaction Steps

By the general method described in Part F of Example 30, 4-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-1-phenylbutan-1-one was reacted with hydroxylamine hydrochloride to provide 4-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-1-phenylbutan-1-one oxime in about a 10 to 1 mixture of E and Z isomers as white crystals after recrystallization from methanol, mp 242-244° C.

Provenance & Evidence