O-Methylhydroxylamine hydrochloride → HCID 72448492, compound

Participants

Reaction Steps

By the general method described in Part F of Example 30, 4-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-1-phenylbutan-1-one was reacted with O-methylhydroxylamine hydrochloride to provide 4-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)-1-phenylbutan-1-one O-methyloxime) in about an 8.7 to 1 mixture of E and Z isomers as a yellow solid after recrystallization from methanol, mp 198-200° C.

Provenance & Evidence