O-Methylhydroxylamine hydrochloride → HCID 72448482, compound

Participants

Reaction Steps

By the general method described in Part F of Example 30, 5-(4-amino-2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)pentan-2-one was reacted with O-methylhydroxylamine hydrochloride to provide 5-(4-amino-2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)pentan-2-one O-methyloxime in about a 5.25 to 1 mixture of E and Z isomers as white needles after recrystallization from toluene, mp 158-161° C.

Provenance & Evidence