O-Methylhydroxylamine hydrochloride → HCID 72448491, compound

Participants

Reaction Steps

By the general method described in Part F of Example 30, 5-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)pentan-2-one was reacted with O-methylhydroxylamine hydrochloride to provide 5-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)pentan-2-one O-methyloxime in about a 7.9 to 1 mixture of E and Z isomers as light brown crystals after recrystallization from aqueous methanol, mp 157-159° C.

Provenance & Evidence