Hydroxyamine hydrochloride → HCID 72448486, compound

Participants

Reaction Steps

By the general method described in Part F of Example 30, 5-(4-amino-2-ethoxymethyl-1H-imidazo[4,5-c]quinolin-1-yl)pentan-2-one was reacted with hydroxylamine hydrochloride to provide 5-(4-amino-2-ethoxymethyl-1H-imidazo[4,5-c]quinolin-1-yl)pentan-2-one oxime in about a 3.5 to 1 mixture of E and Z isomers as a white solid after recrystallization from a mixture of toluene and methanol, mp 220-223° C.

Provenance & Evidence