Hydroxyamine hydrochloride → HCID 72448480, compound

Participants

Reaction Steps

By the general method described in Part F of Example 30, 1-(4-amino-2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)-6-methylheptan-4-one was reacted with hydroxylamine hydrochloride to provide 1-(4-amino-2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)-6-methylheptan-4-one oxime in about a 5 to 1 mixture of E and Z isomers as a white solid after recrystallization from aqueous methanol, mp 207-209° C.

Provenance & Evidence