O-Methylhydroxylamine hydrochloride → HCID 72448477, compound

Participants

Reaction Steps

By the general method described in Part F Example 30, 5-(4-amino-2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)-4,4-dimethylpentan-2-one was reacted with O-methylhydroxylamine hydrochloride to provide 5-(4-amino-2-methyl-1H-imidazo[4,5-c]quinolin-1-yl)-4,4-dimethylpentan-2-one O-methyloxime as about a 4.9 to 1 mixture of E and Z isomers as light yellow needles after recrystallization from aqueous methanol, mp 193-195° C.

Provenance & Evidence