2,6-Dimethyl-4-pyranone → (2R,6S)-2,6-dimethyloxan-4-one

Participants

Reaction Steps

A solution of 2,6-dimethyl-4H-pyran-4-one (2 g, 16.1 mmol) in 20 ml ethanol was stirred over 10% Pd/C (0.2 g) under hydrogen (15 psi) for 16 hours at ambient temperature. TLC showed two spots; one was desired product and second one was side product in a 1:1 ratio. GCMS M+128 for product, and M+130 for side product.

Provenance & Evidence