1-Chloro-4-iodobenzene → HCID 51033435, compound

Participants

Reaction Steps

The title compound was prepared in analogy to Example 5 starting from 1-chloro-4-iodo-benzene (commercially available) and 3-{[(2-fluoro-phenyl)-(3-phenyl-propynoyl)-amino]-methyl}-benzoic acid methyl ester. 1H NMR (300 Hz, CDCl3): δppm 3.88 (s, 3H), 5.11 (s, 2H), 6.22 (d, 1H), 6.61-6.67 (m, 1H), 6.82-6.89 (dd, 1H), 7.26-7.43 (m, 10H), 7.52 (d, 1H), 7.92 (d, 1H), 8.01 (s, 1H).

Provenance & Evidence