Iodobenzene → 3-(3-Benzhydrylidene-2-oxo-2,3-dihydro-indol-1-ylmethyl)-benzoic acid methyl ester

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Reaction Steps

The title compound was prepared in analogy to Example 5 starting from iodo-benzene (commercially available) and 3-{[phenyl-(3-phenyl propynoyl)-amino]-methyl}-benzoic acid methyl ester. 1H NMR (CDCl3, 300 MHz) δppm 8.01 (s, 1H), 8.00 (d, 1H), 7.93 (d, 1H), 7.33-7.52 (m, 12H), 7.05 (dt, 1H), 6.66 (m, 2H), 6.43 (d, 2H), 4.96 (s, 2H), 3.91 (s, 3H).

Provenance & Evidence