4-Iodoanisole → 3-{3-[1-(4-Methoxy-phenyl)-1-phenyl-meth-(E)-ylidene]-2-oxo-2,3-dihydro-indol-1-ylmethyl}-benzoic acid methyl ester

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Reaction Steps

The title compound was prepared in analogy to Example 5 starting from 1-iodo 4-methoxy-benzene (commercially available) and 3-{[phenyl-(3-phenyl propynoyl)-amino]-methyl}-benzoic acid methyl ester. 1H NMR (CDCl3, 300 MHz) δppm 8.01 (s, 1H), 7.94 (d, 1H), 7.49 (d, 1H), 7.26-7.38 (m, 8H), 7.06 (m, 1H), 6.94 (m, 2H), 6.63-6.70 (m, 3H), 4.97 (s, 2H), 3.91 (s, 3H), 3.88 (s, 3H).

Provenance & Evidence