HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodobenzonitrile → 3-{3-[1-(4-Cyano-phenyl)-1-phenyl-meth-(E)-ylidene]-2-oxo-2,3-dihydro-indol-1-ylmethyl}-benzoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodobenzonitrile | HCID 76467 | — |
| Reactant | 3-{[Phenyl-(3-phenyl propynoyl)-amino]-methyl}-benzoic acid methyl ester | HCID 67036155 | — |
| Product | 3-{3-[1-(4-Cyano-phenyl)-1-phenyl-meth-(E)-ylidene]-2-oxo-2,3-dihydro-indol-1-ylmethyl}-benzoic acid methyl ester | HCID 51033548 | — |
Reaction Steps
The title compound was prepared in analogy to Example 5 starting from 4-iodo-benzonitrile (commercially available) and 3-{[phenyl-(3-phenyl propynoyl)-amino]-methyl}-benzoic acid methyl ester. 1H NMR (CDCl3, 300 MHz) δppm 8.00 (s, 1H), 7.93 (d, 1H), 7.74-7.76 (m, 2H), 7.35-7.51 (m, 9H), 7.10 (t, 1H), 6.56-6.72 (m, 2H), 6.35 (d, 1H), 4.95 (s, 2H), 3.91 (s, 3H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08778973B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-422791272dfd47eb85b592dd1043ed4e |
| Source note | uspto-grants-2014_07 |