Benzene, 1-iodo-4-(trifluoromethyl)- → 3-{2-Oxo-3-[1-phenyl-1-(4-trifluoromethyl-phenyl)-meth-(E)-ylidene]-2,3-dihydro-indol-1-ylmethyl}-benzoic acid methyl ester

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Reaction Steps

The title compound was prepared in analogy to Example 5 starting from 1-iodo-4-trifluoromethyl-benzene (commercially available) and 3-{[phenyl-(3-phenyl propynoyl)-amino]-methyl}-benzoic acid methyl ester. 1H NMR (300 Hz, CDCl3) δppm 3.91 (s, 3H), 4.96 (s, 2H), 6.37 (d, 1H), 6.67 (dd, 2H), 7.08 (t, 1H), 7.35-7.40 (m, 7H), 7.49 (d, 2H), 7.71 (d, 2H), 7.95 (d, 1H), 8.01 (s, 1H).

Provenance & Evidence