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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1623445Generated: October 31, 2026

1,2-Difluoro-4-iodobenzene → HCID 51033657, compound

https://huagongshe.com/reaction/1623445

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-Difluoro-4-iodobenzeneHCID 2724444—
Reactant3-{[Phenyl-(3-phenyl propynoyl)-amino]-methyl}-benzoic acid methyl esterHCID 67036155—
ProductHCID 51033657HCID 51033657—

Reaction Steps

The title compound was prepared in analogy to Example 5 starting from 1,2-difluoro-4-iodo-benzene (commercially available) and 3-{[phenyl-(3-phenyl propynoyl)-amino]-methyl}-benzoic acid methyl ester. 1H NMR (300 Hz, CDCl3): δppm 3.90 (s, 3H), 4.96 (s, 2H), 6.58 (d, 1H), 6.70 (m, 2H), 7.07-7.32 (m, 4H), 7.34-7.43 (m, 6H), 7.50 (d, 1H), 7.94 (d, 1H), 8.02 (s, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778973B2
Source datasetuspto-grants-2014_07
ORD IDord-f9e0288cf13f44f8accecd6abcf65fe5
Source noteuspto-grants-2014_07