Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1623460Generated: November 3, 2026

Benzene, 1-iodo-3-(trifluoromethyl)- → HCID 58201657, compound

https://huagongshe.com/reaction/1623460

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-iodo-3-(trifluoromethyl)-HCID 67868—
Reactant3-{[Phenyl-(3-phenyl propynoyl)-amino]-methyl}-benzoic acid methyl esterHCID 67036155—
ProductHCID 58201657HCID 58201657—

Reaction Steps

The title compound was prepared in analogy to Example 5 starting from 1-iodo-3-trifluoromethyl-benzene (commercially available) and 3-{[phenyl-(3-phenyl propynoyl)-amino]-methyl}-benzoic acid methyl ester. 1H NMR (CDCl3, 300 MHz) δppm 8.01 (s, 1H), 7.95 (d, 1H), 7.72 (d, 1H), 7.50-7.63 (m, 3H), 7.36-7.42 (m, 4H), 7.08 (t, 1H), 6.64-6.68 (m, 2H), 6.42 (d, 1H), 4.96 (s, 2H), 3.91 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08778973B2
Source datasetuspto-grants-2014_07
ORD IDord-d0d3ca05223d46ccb4fddead117de632
Source noteuspto-grants-2014_07