4-Cyanophenylboronic acid → HCID 51034672, compound

Participants

Reaction Steps

The title compound was prepared in analogy to Example 84 starting from 4-cyano-phenylboronic acid (commercially available) and 3-{[(4,4-dimethyl-pent-2-ynoyl)-(2-iodo-phenyl)-amino]-methyl}-benzoic acid methyl ester. 1H NMR (400 MHz, DMSO-d6) δppm 1.35 (s, 9H) 3.84 (s, 3H) 5.07 (s, 2H) 5.19 (d, J=7.83 Hz, 1H) 6.56 (t, J=7.71 Hz, 1H) 6.88 (d, J=7.83 Hz, 1H) 7.06 (t, J=7.71 Hz, 1H) 7.42 (d, J=8.08 Hz, 2H) 7.50 (t, J=7.71 Hz, 1H) 7.59 (d, J=7.58 Hz, 1H) 7.87 (d, J=7.58 Hz, 1H) 7.95-8.05 (m, 3H).

Provenance & Evidence