Dichloromethane → Trimethylsilyl 1-(2-chloroacetyl)-4-trimethylsilyloxypyrrolidine-2-carboxylate

HRID 162354Notes

Reaction equation

HRID 162354 reaction equation
[CH3:1][Si:2]([N:3]1[CH:4]([C:13](=[O:14])[O:15][Si:16]([CH3:17])([CH3:18])[CH3:19])[CH2:5][CH:6]([O:8][Si:9]([CH3:10])([CH3:11])[CH3:12])[CH2:7]1)([CH3:20])[CH3:21].[Cl:22][CH2:23][C:24](=[O:25])[F:26].[Cl:27][CH2:28][Cl:29]>>[N:3]1([C:24]([CH2:23][Cl:22])=[O:25])[CH:4]([C:13](=[O:14])[O:15][Si:16]([CH3:17])([CH3:18])[CH3:19])[CH2:5][CH:6]([O:8][Si:9]([CH3:10])([CH3:11])[CH3:12])[CH2:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 615392L-Proline, 1-(trimethylsilyl)-4-[(trimethylsilyl)oxy]-, trimethylsilyl ester, trans-HCID 53254852-chloroacetyl Fluoride

Product 1

HCID 66996939Trimethylsilyl 1-(2-chloroacetyl)-4-trimethylsilyloxypyrrolidine-2-carboxylate

Sources & evidence

ORD record
ord-81808be0fcf64124bd3003b7949a6167
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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