HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2-Acetoxymethyl-3-methyl-4-propoxy-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2,3-Dimethyl-4-propoxypyridine 1-oxide | HCID 15035537 | — |
| Product | 2-Acetoxymethyl-3-methyl-4-propoxy-pyridine | HCID 68468947 | 111.2% |
Reaction Steps
To 20.3 g of 4-propoxy-2,3-dimethylpyridine-1-oxide, 44.0 g (4.0 eq.) of acetic anhydride was added, and the mixture was allowed to react for 4 hours at 90° C. Acetic anhydride was distilled off, and then the resulting concentrated residue was purified on a silica gel column, to obtain 27.8 g of 2-acetoxymethyl-3-methyl-4-propoxy-pyridine as an oily matter.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08778975B2 |
| Source dataset | uspto-grants-2014_07 |
| ORD ID | ord-c203c1efd1c54484ab6c0daecdce4cf4 |
| Source note | uspto-grants-2014_07 |