Acetic Anhydride → HCID 68469332, compound

Participants

Reaction Steps

To 26.7 g (0.11 mol, 1.0 eq.) of 4-pentyloxy-2,3-dimethylpyridine-N-oxide, 44.0 g (0.43 mol, 4.0 eq.) of acetic anhydride was added, and the mixture was allowed to react for 7 hours at 90 to 100° C. Acetic anhydride was distilled off, and then the resulting concentrated residue was purified on a silica gel column, to obtain 22.0 g of 4-pentyloxy-2-acetoxymethyl-3-methylpyridine as an oily matter (yield 79.6%).

Provenance & Evidence