Acetic Anhydride → HCID 68468350, compound

Participants

Reaction Steps

To 32.6 g (0.1 mol, 1.0 eq.) of 4-hexyloxy-2,3-dimethylpyridine-N-oxide, 40.8 g (0.4 mol, 4.0 eq.) of acetic anhydride was added, and the mixture was allowed to react for 5 hours at 87 to 93° C. Acetic anhydride was distilled off, and then the resulting concentrated residue was purified on a silica gel column, to obtain 17.6 g of 4-hexyloxy-2-acetoxymethyl-3-methylpyridine as an oily matter (yield 74.3%).

Provenance & Evidence