Acetic Anhydride → HCID 68467907, compound

Participants

Reaction Steps

To 41.2 g (0.1 mol, 1.0 eq.) of 4-decyloxy-2,3-dimethylpyridine-N-oxide, 40.8 g (0.4 mol, 4.0 eq.) of acetic anhydride was added, and the mixture was allowed to react for 8.5 hours at 88 to 92° C. Acetic anhydride was distilled off, and then the resulting concentrated residue was purified on a silica gel column, to obtain 19.8 g of 4-decyloxy-2-acetoxymethyl-3-methylpyridine as a black brown oily matter (total yield of two processes 61.7%).

Provenance & Evidence