Sodium Hydroxide → HCID 68469285, compound

Participants

Reaction Steps

18.6 g (0.058 mol, 1.0 eq.) of 4-decyloxy-2-acetoxymethyl-3-methylpyridine was added dropwise to a 20% aqueous solution of sodium hydroxide (23 g) at 11 to 22° C., and the mixture was allowed to react for one hour at room temperature. Subsequently, water (93 mL) was added, and then the mixture was extracted with toluene (130 mL). The extract was washed with water, dried over anhydrous magnesium sulfate, and then concentrated to dryness, to obtain 20.6 g of 4-decyloxy-2-hydroxymethyl-3-methylpyridine as a brown oily matter.

Provenance & Evidence