Thionyl Chloride → HCID 68468291, compound

Participants

Reaction Steps

14.5 g (0.061 mol, 1.0 eq.) of 4-heptyloxy-2-hydroxymethyl-3-methylpyridine was dissolved in 700 mL of chloroform, and 37.0 g (0.311 mol, 5.1 eq.) of thionyl chloride was added dropwise at 22 to 30° C. Subsequently, the mixture was heated to reflux for 30 minutes and then concentrated, to obtain 28.2 g of 4-heptyloxy-2-chloromethyl-3-methylpyridine as a black oily matter.

Provenance & Evidence