Benzyl Bromide → HCID 21544507, compound

Participants

Reaction Steps

Potassium carbonate (690 mg, 5.00 mmol) was added to a stirred solution of 2-hydroxy-5-(methyloxy)benzoic acid (336 mg, 2.00 mmol) in acetone (20 ml) followed by the addition of ((bromomethyl)benzene (854 mg, 5.00 mmol). The mixture was refluxed for 12 h and then cooled to room temperature. The mixture was filtered and the filtrate was concentrated to a yellow solid. Flash chromatography over silica gel eluting with 1:10 ethyl acetate:petroleum ether yielded the title compound as a pure, white powder. 500 mg.

Provenance & Evidence