Benzyl Bromide → HCID 53694565, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 5-fluoro-2-hydroxybenzoic acid (468 mg, 3 mmol), potassium carbonate (1037 mg, 7.50 mmol) and (bromomethyl)benzene (1283 mg, 7.50 mmol) in acetone (60 ml) was stirred at 50° C. overnight. The mixture was cooled and filtered. The filtrate was concentrated and the crude product was purified by silica gel chromatography, eluting with hexane:ethyl acetate (10:1) to yield the title compound as a colourless oil. 860 mg.

Provenance & Evidence