1,2-Dichloroethane → HCID 68108450, compound

Participants

Reaction Steps

To a solution of crude 4-{[(4-fluorophenyl)methyl]oxy}-3-[(3-pyridinylamino)carbonyl]benzoic acid (may be prepared as described in Description 111; 62 mg, 0.17 mmol) in N,N-dimethylformamide (DMF) (5 ml) was added morpholine (0.03 ml, 0.34 mmol), EDC (38.9 mg, 0.20 mmol), HOBT (41.5 mg, 0.27 mmol) and N-ethylmorpholine (0.04 ml, 0.34 mmol). The mixture was stirred at room temperature overnight. The mixture was evaporated and the residue was purified by MDAP.

Provenance & Evidence