Cumylamine → HCID 86669647, compound

HRID 1623895Notes

Reaction equation

[CH:1]([N:4]1[C:11]2[C@@H:10]3[CH2:12][C@@H:9]3[CH2:8][C:7]=2[C:6]([C:13]([OH:15])=O)=[N:5]1)([CH3:3])[CH3:2].[C:16]1([C:22]([NH2:25])([CH3:24])[CH3:23])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH3:23][C:22]([NH:25][C:13]([C:6]1[C:7]2[CH2:8][C@H:9]3[CH2:12][C@H:10]3[C:11]=2[N:4]([CH:1]([CH3:2])[CH3:3])[N:5]=1)=[O:15])([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH3:24]

Participants

Reactant 2

HCID 68509Cumylamine

HCID 68182292(4aR,5aR)-4,4a,5,5a-Tetrahydro-1-(1-methylethyl)-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid

Product 1

HCID 86669647HCID 86669647, compound

Procedure

The title compound was prepared in a manner similar to that described in Method G, using (1aR,5aR)-2-Isopropyl-1a,2,5,5a-tetrahydro-1H-2,3-diazacyclopropa[a]pentalene-4-carboxylic acid and 2-phenylpropan-2-amine. LCMS m/z=324.6 [M+H]+.

Sources & evidence

ORD record: ord-bc6e96689995475a90fd135ea6a32ffd
Source dataset: uspto-grants-2014_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08778950B2

Reaction notes

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